Wollastonite/TCP composites for bone regeneration: systematic review and meta-analysis

Wollastonite/TCP composites for bone regeneration: systematic review and meta-analysis

Blog Article

Abstract Composite biomaterials have gained notoriety in recent decades due to the ability to combine desirable properties of each material.Thus, associating bioactivity of wollastonite (W) with biodegradability of tricalcium phosphate (TCP) becomes promising for here bone repair.Therefore, this study investigated, through systematic review and meta-analysis, in vivo studies that evaluated histomorphometrically the bone repair after implantation of W/TCP composites.

The searches were performed in the PubMed/MEDLINE, LILACS/BIREME/Virtual Health Library (VHL), and Scientific Electronic Library Online (SciELO) databases.A total of 312 studies were identified in the databases, of which 6 were included.In data comparison, it was considered the percentage of neoformed bone (NB).

Composites with a higher percentage of W and/or in the scaffold format presented higher NB.These results suggested that the association of these two materials, as well as the porous scaffold format, was determinant replica beach walk candle on NB, which makes these new composites potential for clinical use.